Pulsed Field Ablation

Doylestown Health’s Woodall Center for Heart and Vascular Care offers Pulsed Field Ablation (PFA) to treat atrial fibrillation (AFib). Studies show that this next-level treatment safely eliminates abnormal electrical signals that cause an erratic heartbeat without damaging surrounding tissue.

What is Pulsed Field Ablation?

Pulsed Field Ablation is a cardiac ablation system used to treat AFib.

Also known as an irregular heartbeat or arrhythmia, AFib affects over 59 million people worldwide. AFib occurs when abnormal electrical signals cause the upper chambers of your heart to beat irregularly. This affects blood flow through your heart and can lead to serious health complications, including stroke, without early intervention.

How Does Pulsed Field Ablation Work?

During this minimally invasive procedure, your electrophysiologist (heart rhythm expert) delivers pulsed electric fields (energy) through a catheter to interrupt electrical pathways in your heart that trigger atrial fibrillation. The pulses of energy create scar tissue, which blocks the faulty signals because scar tissue does not conduct electricity.

Traditional forms of ablation use heating or cooling methods to scar the heart tissue. Pulsed Field Ablation uses a nonthermal approach and targets heart tissue without damaging the surrounding tissue in the esophagus, aorta, and lungs.

The heart continues to beat, therefore cardiopulmonary bypass is not required.

Does Doylestown Health Take Part in Pulsed Field Ablation Research?

Our electrophysiologists (heart rhythm experts) engage in research to promote the advancement of safe and effective care for our community. Here is a list of pulsed field ablation studies including those open to enrollment, ongoing, and recently closed.

Now Enrolling

VOLT-AF IDE

A pre-market, prospective, non-randomized, multicenter clinical study to demonstrate safety and effectiveness for the treatment of symptomatic, recurrent, drug-refractory paroxysmal atrial fibrillation and persistent atrial fibrillation. NCT06223789

  • Opens to enrollment last week of June 2024

PULSAR

A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the GlobeĀ® Pulsed Field System for Treating Patients with Symptomatic Paroxysmal or Persistent Atrial Fibrillation. NCT05462145

  • Next arm of enrollment begins mid-end September 2024

Ongoing

No Longer Accepting Participants

ADVANTAGE AF

A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation. NCT05443594

Recently Closed

SPHERE Per-AF

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System. NCT05120193

 ADVENT

The FARAPULSE ADVENT PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation. NCT04612244

 PULSED AF

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF. NCT04198701

Learn More

If you have questions about medical research or about the studies we are doing at Doylestown Health, please visit Clinical Trials/Medical Research or call our Medical Research Office at 215.345.2119.

Does Doylestown Health Take Part in Pulsed Field Ablation Research?

Our electrophysiologists (heart rhythm experts) engage in research to promote the advancement of safe and effective care for our community. Here is a list of pulsed field ablation studies including those open to enrollment, ongoing, and recently closed.

VOLT-AF IDE

A pre-market, prospective, non-randomized, multicenter clinical study to demonstrate safety and effectiveness for the treatment of symptomatic, recurrent, drug-refractory paroxysmal atrial fibrillation and persistent atrial fibrillation. NCT06223789

  • Opens to enrollment last week of June 2024

PULSAR

A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the GlobeĀ® Pulsed Field System for Treating Patients with Symptomatic Paroxysmal or Persistent Atrial Fibrillation. NCT05462145

  • Next arm of enrollment begins mid-end September 2024

No Longer Accepting Participants

ADVANTAGE AF

A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation. NCT05443594

SPHERE Per-AF

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System. NCT05120193

 ADVENT

The FARAPULSE ADVENT PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation. NCT04612244

 PULSED AF

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF. NCT04198701

If you have questions about medical research or about the studies we are doing at Doylestown Health, please visit Clinical Trials/Medical Research or call our Medical Research Office at 215.345.2119.

Our PFA Team

The following electrophysiologists perform pulsed field ablation:
John D. Harding
John D. Harding, MD
Cardiology, Electrophysiology
Practice Location
599 West State Street
Doylestown, PA 18901
Irfan M. Khurram
Irfan M. Khurram, MD
Electrophysiology, Cardiology
Practice Location
315 West State Street
Doylestown, PA 18901
Robert M. Sangrigoli
Robert M. Sangrigoli, MD
Cardiology, Electrophysiology
Practice Location
599 West State Street
Doylestown, PA 18901
Philip C. Wiener
Philip C. Wiener, DO
Cardiology, Electrophysiology
Practice Location
599 West State Street
Doylestown, PA 18901